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dnam 1 fc  (R&D Systems)


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    Structured Review

    R&D Systems dnam 1 fc
    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and <t>DNAM-1-Fc,</t> respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Dnam 1 Fc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+dnam+1+fc/Recombinant+Human+DNAM-1%2FCD226+Fc+Chimera+Protein%2C+CF/bio_rxiv__64898__2026__03__03__708729-181-14-15
    Average 94 stars, based on 6 article reviews
    dnam 1 fc - by Bioz Stars, 2026-09
    94/100 stars

    Images

    1) Product Images from "Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I"

    Article Title: Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I

    Journal: bioRxiv

    doi: 10.64898/2026.03.03.708729

    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and DNAM-1-Fc, respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.
    Figure Legend Snippet: (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and DNAM-1-Fc, respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.

    Techniques Used:

    Related Articles

    Recombinant:

    Article Title: The combination of type I IFN, TNF-α, and cell surface receptor engagement with dendritic cells enables NK cells to overcome immune evasion by dengue virus.
    Article Snippet: F(ab9)2 fragments of blocking Ab against Fas (clone ZB4; Millipore) and its isotype control (clone P3.6.2.8.1; eBioscience) were generated using the F(ab9)2 Preparation Kit (Pierce Biotechnology). .. Recombinant human DNAM-1-Fc, NKG2D-Fc, NKp30-Fc, NKp44-Fc, NKp46-Fc, NKp80-Fc fusion proteins, and human IgG1-Fc control protein were purchased (R&D Systems). .. Cellular binding of the receptor-Fc proteins was detected using PE-conjugated F(ab9)2 fragments of donkey anti-human IgG (Jackson ImmunoResearch Laboratories).

    Control:

    Article Title: The combination of type I IFN, TNF-α, and cell surface receptor engagement with dendritic cells enables NK cells to overcome immune evasion by dengue virus.
    Article Snippet: F(ab9)2 fragments of blocking Ab against Fas (clone ZB4; Millipore) and its isotype control (clone P3.6.2.8.1; eBioscience) were generated using the F(ab9)2 Preparation Kit (Pierce Biotechnology). .. Recombinant human DNAM-1-Fc, NKG2D-Fc, NKp30-Fc, NKp44-Fc, NKp46-Fc, NKp80-Fc fusion proteins, and human IgG1-Fc control protein were purchased (R&D Systems). .. Cellular binding of the receptor-Fc proteins was detected using PE-conjugated F(ab9)2 fragments of donkey anti-human IgG (Jackson ImmunoResearch Laboratories).



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    Image Search Results


    (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and DNAM-1-Fc, respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.

    Journal: bioRxiv

    Article Title: Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I

    doi: 10.64898/2026.03.03.708729

    Figure Lengend Snippet: (A) Display of ULBP1 and CD155 on CombiCells detected by mAbs and NKG2D-Fc, and DNAM-1-Fc, respectively. (B&C) KIR2DL1+ and KIR2DL1-NK-cell degranulation (CD107a upregulation) in response to ULBP1, CD155, and HLA-C*05:01 displayed on CombiCells. (C) Three types of HLA-C*05:01 were tested, all containing P2 (IIDKSGSTV); wild-type, open and dipeptide exchanged. Data from three independent experiments with NK cells from separate donors are shown.

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